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2-year postdoc position in inferring gene regulatory network of sunflower

Postdoctoral position  on structure  learning of  transcription factor network related to  heterosis in sunflower available at  the INRA MIAT laboratory in France (near Toulouse)

The  MIAT  laboratory  is  seeking  a  highly-qualified  post-doctoral researcher to work on a project assessing transcription factor network controlling heterosis  of gene expression in  sunflower.  Heterosis is used  by natural  selection  and  mankind to  adapt  plant and  animal organisms  to new  environments or  needs.  However,  the genetic  and molecular bases of heterosis are still poorly known. This project aims to study the role of transcription factor regulations in the heterosis of  gene expressions.  For this  purpose,  the data  consists in  gene expressions  of sunflower  on two  genetic designs  with one  over 400 hybrids and their associated genotypes.

The main  objective of this  post-doctoral appointment will be  to (i) select  transcripts  whose  expression  in  hybrids  is  significantly superior  to the  parental  mean, (ii)  collect transcription  factors homologous  to known  TF  in  Arabidopsis, and  (iii)  infer the  gene regulatory  network  of heterosis  between  TFs  and target  genes  by exploiting gene expressions and genotyping data, following a genetical genomics   approach  using   state-of-the-art  statistical   structure
learning methods.

The successful candidate should hold a  PhD with a solid background in statistics  or   computer  science,   and  also  have   experience  in biostatistics, bioinformatics, or  machine learning. Excellent written and spoken skills  in English are a  must. The project is  part of the “Investment      for       the      Future“       SUNRISE      program (http://www.sunrise-project.fr/en/).   The  successful candidate  will
join  a  group  of  three   scientists  working  on  the  project  and approximately   ten   scientists    working   on   biostatistics   and bioinformatics.

The appointment is for 2 years, with a provisional start date of March 2017. Basic gross salary ranges from  3500€ to 3800€ (approx. 2300€ to 2500€ net salary) depending on years of experience.

Candidates that are eligible to  apply for an AgreenSkills+ fellowship could benefit  from attractive  conditions that include  monthly gross salaries, ranging  from 4800€ to  5500€, if their project  proposal is successful. To  find out more  about the  program and whether  you are able  to   apply  for   an  AgreenSkills+  fellowship,   please  visit http://www.agreenskills.eu/ (program finishes in May 2019)

A dynamic  city in  the South-West  of France  famous for  its natural beauty  and rich  history, with  about 100,000 students, Toulouse is among the ten fastest growing urban economies in Europe.

Please send your  CV, cover letter, and (2-3) letters  of reference to simon.de-givry@inra.fr before February 3rd 2017 Object: sunrise post-doctoral application

Posted in Stage / Emploi.



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